Fantasy matchup analysis — how many points the Bills allow to quarterbacks. Updated through the 2025 season. Use this to identify streamers and make start/sit decisions.
Players who have historically scored most against the Buffalo Bills defense:
Last 10 games quarterbacks faced the Buffalo Bills (2024–2025 seasons):
| Game | Player | Fantasy Pts |
|---|---|---|
| S2026 Wk8 | Joe Fagnano BAL |
1.4 |
| S2026 Wk5 | Matthew Stafford LAR |
27.3 |
| S2026 Wk4 | Drake Maye NE |
27.2 |
| S2026 Wk3 | Justin Herbert LAC |
13.7 |
| S2026 Wk2 | Jared Goff DET |
29.8 |
| S2026 Wk1 | C.J. Stroud HOU |
16.5 |
| S2025 Wk18 | Brady Cook NYJ |
9.1 |
| S2025 Wk17 | Jalen Hurts PHI |
8.9 |
| S2025 Wk16 | Shedeur Sanders CLE |
13.2 |
| S2025 Wk15 | Drake Maye NE |
21.5 |
This is matchup context, not a personalized recommendation. Connect your Sleeper, ESPN, or Yahoo league and PlayCaller's AI gives you a start/sit decision based on your exact roster, league scoring, and this week's matchup.
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