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NFL Waiver Wire Week 10 2025 — AI-Powered Pickup Targets

WEEK 10 · 2025 May 30, 2026

Week 10 of the 2025 NFL season delivered a masterclass in running back dominance, with several elite performers putting up monster numbers that shaped the waiver wire landscape. The performances this week established clear tiers of value that savvy fantasy managers could exploit for the stretch run toward the playoffs.

Teams with strong ground games showcased their depth, while unexpected quarterback contributions and receiving standouts offered alternative pathways to production in a week that proved fantasy football remained unpredictable even deep into the season.

Jonathan Taylor (IND) — RB, 49.60 pts

Taylor absolutely demolished defenses with 244 rushing yards and 3 rushing touchdowns, adding 3 receptions for 42 receiving yards. The Colts back put on a clinic, establishing himself as one of the most consistent fantasy assets available on waivers heading into the second half of the season.

Managers who had released or overlooked Taylor found themselves chasing his production for weeks afterward. His Week 10 performance proved he remained a league-winner candidate despite any earlier inconsistencies, and waiver claims for the Colts running back priority wire would have been among the season's most impactful roster moves.

De'Von Achane (MIA) — RB, 40.50 pts

Achane delivered elite production with 174 rushing yards and 2 rushing touchdowns while adding 6 receptions for 51 receiving yards. The Dolphins back demonstrated his dual-threat capability, showcasing the pass-catching prowess that made him such a valuable fantasy asset in Miami's offense.

His performance reinforced the value of Miami's backfield, and waiver pickups of Achane became premium acquisitions for teams seeking high-ceiling running back depth. The combination of volume and efficiency made him one of the most sought-after add-candidates during the post-Week 10 waiver period.

Jahmyr Gibbs (DET) — RB, 38.20 pts

Gibbs contributed 142 rushing yards and 2 rushing touchdowns while recording 3 receptions for 30 receiving yards and 1 receiving touchdown. The Lions running back continued his strong season with a balanced offensive performance that highlighted Detroit's offensive balance.

Waiver wire interest in Gibbs reflected his established role in the Detroit offense, and managers recognized his consistency as a mid-tier RB1 with upside. His Week 10 output confirmed the Lions intended to maintain heavy running back involvement in their offensive scheme.

Davis Mills (HOU) — QB, 28.68 pts

Mills posted 292 passing yards and 2 passing touchdowns while adding 20 rushing yards and 1 rushing touchdown. The Texans quarterback provided immediate value to streaming managers seeking a high-floor pivot option at the position.

Waiver wire targeting of Mills reflected his performance-based value rather than name recognition, and fantasy managers capitalizing on his weekly ceiling found a streamer with consistent upside. His dual-threat ability added floor to an otherwise pedestrian passing stat line.

TreVeyon Henderson (NE) — RB, 28.00 pts

Henderson recorded 147 rushing yards and 2 rushing touchdowns with 1 reception for 3 receiving yards. The Patriots running back demonstrated the touchdown-dependent value profile that made him a waiver wire target despite limited receiving work.

Managers viewed Henderson as a high-variance flex option available through waiver claims, and his Week 10 performance proved that Patriots running back touches could translate to immediate fantasy production. The touchdown ceiling made him a valuable lottery ticket for teams seeking upside.

Trey McBride (ARI) — TE, 27.70 pts

McBride caught 9 receptions for 127 receiving yards and 1 touchdown, establishing himself as a consistent red zone target in Arizona's offense. The Cardinals tight end dominated target share and converted those opportunities into fantasy production.

Waiver wire claims for McBride reflected his elite opportunity profile, and fantasy managers recognized him as a legitimate TE1 option with weekly floor and ceiling. His reception total and efficiency metrics made him one of the week's most valuable tight end pickups.

Matthew Stafford (LAR) — QB, 26.90 pts

Stafford threw for 280 yards and 4 passing touchdowns while recording minus-3 rushing yards. The Rams quarterback delivered excellent volume and efficiency, operating in an aggressive passing scheme that rewarded fantasy managers selecting him for streaming purposes.

Managers targeting Stafford on waivers gained immediate production, and his four-touchdown performance represented the elite ceiling that made him a valuable quarterback option. The volume-based approach in the Rams offense provided consistent weekly opportunity.

Jaxson Dart (NYG) — QB, 26.28 pts

Dart accumulated 242 passing yards and 0 passing touchdowns while adding 66 rushing yards and 2 rushing touchdowns. The Giants quarterback provided waiver wire value through rushing production, demonstrating the dual-threat skills that added floor to his fantasy profile.

Waiver interest in Dart reflected his emerging role with the Giants, and managers seeking quarterback depth gained a player with meaningful rushing upside. His running ability provided differentiation from traditional pocket-passing quarterback options available in deep leagues.

Caleb Williams (CHI) — QB, 25.10 pts

Williams posted 220 passing yards and 1 passing touchdown while recording 63 rushing yards and 1 rushing touchdown. The Bears quarterback continued his sophomore-year development, combining passing and rushing production for solid fantasy output.

Managers viewing Williams as a waiver wire option gained exposure to Chicago's dual-threat quarterback approach, and his rushing upside provided differentiation from the broader quarterback position. His week validated the streaming value available through mobile signal-callers.

Jared Goff (DET) — QB, 24.80 pts

Goff threw for 320 passing yards and 3 passing touchdowns in a controlled offensive performance. The Lions quarterback operated efficiently against his opponent, showcasing the accuracy that made him a reliable fantasy asset.

Waiver wire targeting of Goff reflected Detroit's consistent offensive production, and fantasy managers recognized him as a stable weekly starter rather than an upside-dependent streaming option. His three-touchdown performance validated the high-volume passing approach in the Detroit offense.

Drake London (ATL) — WR, 24.40 pts

London caught 6 passes for 104 receiving yards and 1 touchdown, establishing himself as a consistent option in the Falcons passing attack. The Atlanta receiver provided reliable weekly floor through target volume and efficiency.

Managers adding London through waivers gained a high-volume receiver with consistent opportunity in Arthur Smith's offense. His reception total and receiving production made him a valuable wide receiver depth addition during the waiver period.

Jameson Williams (DET) — WR, 23.90 pts

Williams recorded 6 receptions for 119 receiving yards and 1 receiving touchdown, continuing his role as a primary pass-catcher in Detroit's offense. The Lions receiver demonstrated the explosive upside that made him valuable across all league formats.

Waiver wire interest in Williams reflected his established role as a high-ceiling receiver in Detroit's passing attack, and managers prioritized claiming him as a flex asset with meaningful scoring upside. His receiving production validated the heavy passing involvement in the Lions offense.

Emeka Egbuka (TB) — WR, 23.50 pts

Egbuka caught 6 passes for 115 receiving yards and 1 touchdown, establishing himself as a consistent receiving target in Tampa Bay's offense. The Buccaneers receiver provided reliable weekly production through high target volume.

Managers adding Egbuka on waivers gained a receiver with consistent opportunity and ability to accumulate both receptions and yardage. His performance reflected his role as a primary pass-catching option in the Tampa Bay receiving attack.

George Kittle (SF) — TE, 23.40 pts

Kittle caught 9 receptions for 84 receiving yards and 1 receiving touchdown, demonstrating the pass-catching consistency that made him a top-tier tight end option. The 49ers tight end posted impressive reception totals that translated into fantasy production.

Waiver wire claims for Kittle reflected his elite opportunity profile and proven ability to convert targets into consistent fantasy output. Managers seeking tight end depth gained an asset with weekly floor and ceiling from one of the premier receiving options in San Francisco's offense.

Jalen Nailor (LV) — WR, 23.40 pts

Nailor caught 5 passes for 124 receiving yards and 1 receiving touchdown, showcasing the explosive play ability that made him valuable in deeper league formats. The Raiders receiver provided per-play efficiency that translated into significant fantasy scoring.

Waiver targeting of Nailor reflected his emerging role as a deep threat in Las Vegas's receiving corps, and fantasy managers recognized his upside-dependent value profile. His receiving yardage and touchdown demonstrated his potential as a weekly flex option.

Baker Mayfield (TB) — QB, 22.92 pts

Mayfield completed passes for 273 yards and 3 touchdowns, operating efficiently in Tampa Bay's passing attack. The Buccaneers quarterback continued his reliable fantasy production through consistent touchdown generation.

Managers adding Mayfield through waivers gained access to a quarterback with solid weekly floor through touchdown upside. His three-touchdown performance validated his role as a consistent starter in Tampa Bay's offense heading into the second half of the season.

Nico Collins (HOU) — WR, 22.60 pts

Collins recorded 7 receptions for 136 receiving yards, establishing himself as the primary receiving target in Houston's offense. The Texans receiver dominated target volume and converted those opportunities into significant yardage production.

Waiver wire interest in Collins reflected his high-volume receiving role, and fantasy managers prioritized claiming him as a wide receiver depth option with consistent weekly opportunity. His reception total demonstrated his elite target share in the Houston receiving attack.

Kyren Williams (LAR) — RB, 22.40 pts

Williams recorded 73 rushing yards and 2 rushing touchdowns with 2 receptions for 11 receiving yards. The Rams running back provided touchdown-dependent value that made him a useful flex option despite moderate rushing volume.

Managers adding Williams on waivers gained exposure to red zone opportunity in Los Angeles's offense, and his two-touchdown performance justified his role as a backup running back with meaningful scoring ceiling. His conversion of limited volume into touchdowns made him a useful waiver wire acquisition.

Chris Olave (NO) — WR, 21.40 pts

Olave caught 5 passes for 104 receiving yards and 1 receiving touchdown, continuing his role as a primary receiving option in New Orleans's offense. The Saints receiver provided reliable per-target production that translated into consistent fantasy output.

Waiver wire targeting of Olave reflected his established role in the Saints passing attack, and fantasy managers recognized him as a high-volume receiver with consistent weekly opportunity. His receiving production validated his position as a primary pass-catching option in New Orleans's offensive scheme.

Full 2025 NFL Season Archive

PlayCaller maintains comprehensive historical performance data from the entire 2025 NFL season, allowing fantasy managers to analyze waiver wire decisions and league trends across all 18 weeks. Visit playcallerapp.com to explore detailed statistics and optimize roster construction strategies for future fantasy football competition.

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