PLAYCALLER
Isaac Guerendo
RB

Isaac Guerendo

SF active

Isaac Guerendo is a RB for the SF (NFL). Currently active. Isaac is a running back target monitored by PlayCaller for fantasy add/drop and start/sit decisions.

Frequently Asked Questions

Is Isaac Guerendo playing this week?
As of November 3, 2026, no injury designation has been reported for Isaac Guerendo. He is expected to be available this week.
Should I start Isaac Guerendo in fantasy football this week?
Isaac Guerendo scored 1.0 fantasy points in his most recent game. Start/sit decisions should also account for the current matchup and your league's scoring format.
What is Isaac Guerendo's injury status?
As of November 3, 2026, no injury designation has been reported for Isaac Guerendo. He is listed as active.
How has Isaac Guerendo been performing recently?
Isaac Guerendo's recent fantasy output: Wk 13: 1.0 pts vs CLE; Wk 17: 13.9 pts vs DET; Wk 15: 11.5 pts vs LAR.
Is Isaac Guerendo worth a waiver claim?
Isaac Guerendo's waiver value depends on roster needs, current injury status, and remaining schedule. See PlayCaller's waiver wire section for a current add/drop recommendation.
Recent Performance

Season Totals

SeasonGamesTotal FPTSAvg FPTSPass YdsRush YdsRecTD
2025 1 GP 1.0 1.0/g avg — — — —
2024 9 GP 95.7 10.6/g avg — 415 15 4

Game Log

WeekOppFPTSPass YdsRush YdsRecTD
2025 Season
Wk 13 CLE 1.0 — — — —
2024 Season
Wk 17 DET 13.9 — 34 4 —
Wk 15 LAR 11.5 — 57 4 —
Wk 14 CHI 26.8 — 78 2 2
Wk 13 BUF 8.6 — 19 1 1
Wk 8 DAL 19.2 — 85 3 1
Wk 7 KC 1.7 — 2 1 —
Wk 6 SEA 9.9 — 99 — —
Wk 5 ARI 2.2 — 22 — —
Wk 3 LAR 1.9 — 19 — —

Isaac Guerendo has been consistent, for better or worse.

Compare & Matchups
This week's RB matchup →Isaac Guerendo vs Brock Purdy →Isaac Guerendo vs Christian McCaffrey →Isaac Guerendo vs Mac Jones →
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