As of September 9, 2026, the NFL offseason has given way to the cusp of the regular season, and fantasy managers who tracked NFL free agency and depth-chart developments all summer are about to see their homework pay off. The signals coming out of final injury reports and roster evaluations are shaping how rosters should be constructed heading into Week 1. From quarterback health updates to backfield shakeups, here is what you need to know before locking in your 2026 fantasy lineups.