With the fantasy baseball playoffs on the line for many managers, the September 25, 2026 MLB injury report is loaded with roster-altering news. Your fantasy baseball waiver wire decisions this week could make or break your championship run, so let's break down the five biggest player signals you need to act on right now. From Detroit to Houston to Atlanta, the MLB player news cycle is moving fast and PlayCaller has you covered.

Colt Keith (DET): Season-Ending Injury

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